Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598261 | 0.96 | CHRM1 (0.50) | CHRM1CHRM5CHRM3RENEGFR | |
| SCHEMBL8602365 | 0.92 | CHRM1 (0.47) | CHRM1CHRM5CHRM3RENEGFR | |
| SCHEMBL29901598 | 0.88 | CHRM1 (0.46) | CHRM1CHRM5CHRM3RENEGFR | |
| SCHEMBL8600207 | 0.87 | RORC (0.43) | CHRM1CHRM5CHRM3POLB | |
| SCHEMBL10592910 | 0.85 | CHRM1 (0.45) | CHRM1CHRM5CHRM3RENEGFR | |
| SCHEMBL29901589 | 0.85 | CHRM1 (0.43) | CHRM1CHRM5CHRM3EGFR | |
| SCHEMBL29901581 | 0.84 | REN (0.44) | CHRM1CHRM5CHRM3RENDRD2 | |
| SCHEMBL8878855 | 0.81 | CHRM1 (0.41) | CHRM1CHRM5CHRM3SLC5A1SLC5A2 | |
| SCHEMBL10431134 | 0.80 | HTT (0.47) | CHRM1POLBCYP1A2CYP2C19 | |
| SCHEMBL8600208 | 0.79 | CYP11B2 (0.42) | CHRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |