Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847726 | 0.97 | KDM4E (0.50) | KDM4EMAPTGAAALDH1A1HPGD | |
| SCHEMBL7770256 | 0.89 | SQOR (0.49) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL2961972 | 0.84 | KDM4E (0.58) | KDM4EMAPTGAAALDH1A1HPGD | |
| SCHEMBL2767895 | 0.83 | CTSS (0.43) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL14007665 | 0.82 | CTSS (0.51) | KDM4EMAPTGAAHPGDLMNA | |
| SCHEMBL12598663 | 0.80 | CTSS (0.46) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL7850867 | 0.77 | ABL1 (0.47) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL18462193 | 0.75 | CTSS (0.57) | KDM4EMAPTGAAALDH1A1HPGD | |
| SCHEMBL1771966 | 0.74 | CTSS (0.53) | KDM4ELMNAMAPK1TDP1L3MBTL1 | |
| SCHEMBL8755201 | 0.74 | MCL1 (0.44) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707603-A | Pyridine complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions | NYCOMED IMAGING AS (NO) | 1998-01-13 | — | — | US | disclosed |