Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993065 | 0.81 | ALDH1A1 (0.56) | DAOPKMPKLRPARP1CYP3A4 | |
| SCHEMBL29904251 | 0.75 | MAPT (0.54) | DAOPARP1CYP3A4NAMPTXDH | |
| SCHEMBL30011 | 0.75 | MAPT (0.54) | DAOPARP1CYP3A4NAMPTXDH | |
| SCHEMBL8487610 | 0.72 | TDP1 (0.50) | DAOPKMPKLRCYP3A4NAMPT | |
| SCHEMBL29993384 | 0.72 | PARP1 (0.73) | DAOPKMPKLRPARP1PSMB8 | |
| SCHEMBL6008297 | 0.72 | PARP1 (0.73) | DAOPKMPKLRPARP1PSMB8 | |
| SCHEMBL30597526 | 0.72 | MAPT (0.54) | CYP3A4NAMPTXDHGRIA1GRIA2 | |
| SCHEMBL28686 | 0.72 | MAPT (0.54) | CYP3A4NAMPTXDHGRIA1GRIA2 | |
| SCHEMBL916214 | 0.71 | ALDH1A1 (0.47) | DAOPKMPKLRPARP1CYP3A4 | |
| SCHEMBL12359788 | 0.71 | ALDH1A1 (0.46) | DAOPKMPKLRPARP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |