Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980781 | 0.86 | CA12 (0.53) | ALDH1A1DAOPARP1GRIA1GRIA2 | |
| SCHEMBL8600209 | 0.81 | DAO (0.50) | ALDH1A1DAOPARP1GRIA1GRIA2 | |
| SCHEMBL30011 | 0.77 | MAPT (0.54) | ALDH1A1DAOPARP1GRIA1GRIA2 | |
| SCHEMBL29904251 | 0.77 | MAPT (0.54) | ALDH1A1DAOPARP1GRIA1GRIA2 | |
| SCHEMBL29236590 | 0.76 | PKM (0.56) | DAOPARP1GRIA1GRIA2GRIA3 | |
| SCHEMBL915292 | 0.76 | ALDH1A1 (0.50) | ALDH1A1DAOPARP1GRIA1GRIA2 | |
| SCHEMBL8487610 | 0.74 | TDP1 (0.50) | ALDH1A1DAOGRIA1GRIA2GRIA3 | |
| SCHEMBL6008297 | 0.74 | PARP1 (0.73) | ALDH1A1DAOPARP1GRIA1GRIA2 | |
| SCHEMBL29993384 | 0.74 | PARP1 (0.73) | ALDH1A1DAOPARP1GRIA1GRIA2 | |
| SCHEMBL1664417 | 0.73 | CYP3A4 (0.66) | ALDH1A1DAOPARP1GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | AUCKLAND UNISERVICES LIMITED | 2010-07-08 | — | — | US | disclosed |
| WO-2008030120-A1 | A METHOD FOR THE FLUORESCENT DETECTION OF NITROREDUCTASE ACTIVITY USING NITRO-SUBSTITUTED AROMATIC COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | BLVRB, POR, CBR3 | ALDH1A1 119/4885DAO 310/4885PARP1 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.