Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603454 | 0.81 | CCR8 (0.34) | MAPTCCR8KMT2A | |
| SCHEMBL17659438 | 0.72 | AHR (0.52) | CSNK2A2CSNK2BCSNK2A1MAPTCCR8 | |
| SCHEMBL8604129 | 0.70 | CCR8 (0.33) | MAPTCCR8KMT2A | |
| SCHEMBL8602787 | 0.69 | MAPT (0.55) | MAPTAHR | |
| SCHEMBL8603592 | 0.68 | RXFP1 (0.38) | MAPTCCR8 | |
| SCHEMBL24787431 | 0.67 | CSNK2A1 (0.42) | CSNK2A2CSNK2BCSNK2A1MAPTCCR8 | |
| SCHEMBL8808071 | 0.65 | KDM4E (0.52) | CSNK2A2CSNK2BCSNK2A1KMT2AAHR | |
| SCHEMBL15102902 | 0.65 | CCR8 (0.40) | CCR8KMT2AAURKATPX2AHR | |
| SCHEMBL31656115 | 0.64 | TRIM24 (0.56) | CSNK2A2CSNK2BCSNK2A1MAPTKMT2A | |
| SCHEMBL26077500 | 0.64 | AURKA (0.38) | CSNK2A2CSNK2BCSNK2A1MAPTCCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |