Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15371410 | 0.76 | CCR8 (0.59) | MAPTPOLBTRIM24TRIM33BRPF1 | |
| SCHEMBL8603454 | 0.76 | CCR8 (0.34) | MAPTALDH1A1POLBGAARXFP1 | |
| SCHEMBL8603311 | 0.76 | HTR2A (0.46) | MAPTALDH1A1POLBGAARXFP1 | |
| SCHEMBL8604191 | 0.76 | GAA (0.35) | MAPTALDH1A1POLBGAARXFP1 | |
| SCHEMBL8601952 | 0.76 | ALDH1A1 (0.38) | MAPTALDH1A1POLBGAARXFP1 | |
| SCHEMBL8808071 | 0.72 | KDM4E (0.52) | ALDH1A1AHRKIF11SMN1; SMN2CYP1A2 | |
| SCHEMBL8600076 | 0.72 | ADRB3 (0.37) | MAPTALDH1A1POLBGAARXFP1 | |
| SCHEMBL8603592 | 0.71 | RXFP1 (0.38) | MAPTALDH1A1POLBGAARXFP1 | |
| SCHEMBL29364263 | 0.70 | AHR (0.56) | ALDH1A1BRPF1AHRCYP2A6AR | |
| SCHEMBL129649 | 0.70 | AHR (0.56) | ALDH1A1BRPF1AHRCYP2A6AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |