Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603454 | 0.78 | CCR8 (0.34) | RXFP1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL8602787 | 0.71 | MAPT (0.55) | RXFP1ALDH1A1POLBGAAMAPT | |
| SCHEMBL8603311 | 0.70 | HTR2A (0.46) | RXFP1ALDH1A1KDM4ENQO2POLB | |
| SCHEMBL26145362 | 0.69 | NQO2 (0.40) | RXFP1ALDH1A1KDM4ECYP19A1NQO2 | |
| SCHEMBL8600224 | 0.68 | CSNK2A2 (0.43) | MAPTCCR8 | |
| SCHEMBL15315856 | 0.68 | KDM4E (0.52) | RXFP1ALDH1A1KDM4ECYP19A1NQO2 | |
| SCHEMBL6270065 | 0.67 | RHEB (0.41) | RXFP1ALDH1A1KDM4EPOLBADRA2A | |
| SCHEMBL30483746 | 0.67 | RHEB (0.41) | RXFP1ALDH1A1KDM4EPOLBADRA2A | |
| SCHEMBL12034737 | 0.67 | PARP1 (0.41) | ALDH1A1KDM4ECYP19A1NQO2 | |
| SCHEMBL26145361 | 0.66 | NQO2 (0.40) | RXFP1ALDH1A1KDM4ECYP19A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |