Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600387 | 0.89 | HDAC6 (0.58) | HDAC6KMT2ARAB9ANPC1POLB | |
| SCHEMBL1379298 | 0.82 | KMT2A (0.52) | HDAC6KMT2ARAB9ANPC1POLB | |
| SCHEMBL29779902 | 0.82 | KMT2A (0.52) | HDAC6KMT2ARAB9ANPC1POLB | |
| Hydrochloric Acid SCHEMBL2958779 | 0.81 | KMT2A (0.51) | HDAC6KMT2ARAB9ANPC1POLB | |
| SCHEMBL5131241 | 0.81 | HDAC6 (0.44) | HDAC6KMT2ARAB9ANPC1POLB | |
| Sulfuric Acid SCHEMBL7332400 | 0.77 | KMT2A (0.48) | HDAC6KMT2ARAB9ANPC1POLB | |
| SCHEMBL2725218 | 0.77 | HDAC6 (0.49) | HDAC6KMT2ARAB9ANPC1POLB | |
| SCHEMBL3776189 | 0.77 | SLC2A1 (0.59) | HDAC6KMT2ARAB9ANPC1POLB | |
| SCHEMBL29424777 | 0.76 | HDAC6 (0.56) | HDAC6KMT2ARAB9ANPC1POLB | |
| SCHEMBL1299107 | 0.76 | HDAC6 (0.56) | HDAC6KMT2ARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871624-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997021703-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-06-19 | — | — | WO | disclosed |