Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776194 | 0.86 | HDAC6 (0.66) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14723284 | 0.85 | HDAC6 (0.44) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27553512 | 0.84 | KDM4E (0.45) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5947 | 0.84 | KDM4E (0.53) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1873286 | 0.83 | RAB9A (0.54) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2725218 | 0.82 | HDAC6 (0.49) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL476588 | 0.82 | AR (0.52) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5770245 | 0.82 | HDAC6 (0.49) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9928726 | 0.82 | KDM4E (0.51) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12647585 | 0.81 | CTNNB1 (0.51) | SLC2A1HDAC6SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981920-B2 | Inhibitors of histone deacetylase | RODIN THERAPEUTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-20170204070-A1 | INHIBITORS OF HISTONE DEACETYLASE | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-07-20 | — | — | US | disclosed |
| US-9684238-B2 | Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator | TOKYO OHKA KOGYO CO., LTD. (JP) | 2017-06-20 | — | — | US | disclosed |
| US-9684238-B2 | Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator | TOKYO OHKA KOGYO CO., LTD. (JP) | 2017-06-20 | — | — | US | disclosed |
| WO-2015200619-A1 | INHIBITORS OF HISTONE DEACETYLASE | RODIN THERAPEUTICS, INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| EP-2947082-A1 | N1-PYRAZOLOSPIROKETONE ACETYL-CoA CARBOXYLASE INHIBITORS | Pfizer Inc (US) | 2015-11-25 | — | — | EP | disclosed |
| US-20150259321-A1 | FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR | DAITO CHEMIX CORPORATION (JP) | 2015-09-17 | — | — | US | disclosed |
| EP-2913323-A1 | FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR | Daito Chemix Corporation (JP) | 2015-09-02 | — | — | EP | disclosed |
| EP-2676958-B1 | N1-Pyrazolospiroketone acetyl-CoA carboxylase inhibitors | PFIZER (US) | 2015-07-01 | — | — | EP | disclosed |
| US-8759539-B2 | Substituted bicyclic amines for the treatment of diabetes | MERCK SHARP & DOHME CORP. (US) | 2014-06-24 | — | — | US | disclosed |
| WO-2009027475-A1 | PHENYLISOQUINOLINE AND PHENYLQUINAZOLINE DERIVATIVES FOR THE TREATMENT OF BONE DISEASES | NOVARTIS AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| US-20080075719-A1 | Method for Augmenting B Cell Depletion | GENENTECH, INC. (US) | 2008-03-27 | — | — | US | disclosed |
| US-20080075719-A1 | Method for Augmenting B Cell Depletion | GENENTECH, INC. (US) | 2008-03-27 | — | — | US | disclosed |
| US-20070099956-A1 | Nitrogen-containing heterocyclic derivatives having 2, 6-disubstituted styryl | ASTELLAS PHARMA INC. AND KOTOBUKI PHARMACEUTICAL CO., LTD. | 2007-05-03 | — | — | US | disclosed |
| US-20070099956-A1 | Nitrogen-containing heterocyclic derivatives having 2, 6-disubstituted styryl | ASTELLAS PHARMA INC. AND KOTOBUKI PHARMACEUTICAL CO., LTD. | 2007-05-03 | — | — | US | disclosed |
| WO-2005113003-A2 | METHOD FOR AUGMENTING B CELL DEPLETION | GENENTECH, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-4960783-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0325802-A1 | Use of benzimidazole derivatives as operating capacity promotors | BAYER AG (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-3986878-A | SILVER HALIDE PHOTOGRAPHIC EMULSION | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-19 | — | — | US | disclosed |
| US-3985563-A | Silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204070-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC2, HDAC1, HDAC5 | SLC2A1 4089/4885HDAC6 4/4885SMN1; SMN2 1222/4885 |
| US-20070099956-A1 | Nitrogen-containing heterocyclic derivatives having 2, 6-disubstituted styryl | SCN1B, CACNA1B, SCN2A | SLC2A1 2679/4885HDAC6 140/4885SMN1; SMN2 118/4885 |
| US-20150259321-A1 | FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR | AFF1, AFF2, FTO | SLC2A1 4349/4885HDAC6 3742/4885SMN1; SMN2 3169/4885 |
| US-20080075719-A1 | Method for Augmenting B Cell Depletion | CD22, ITGAM, FCGR3B | SLC2A1 1670/4885HDAC6 576/4885SMN1; SMN2 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.