SCHEMBL8600458

SCHEMBL8600458

[CH2]CSCCn1ccnc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 6/20 0.52
TP53 P04637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TSHR P16473 1/20 0.47
EGLN3 Q9H6Z9 1/20 0.44
ALDH1A1 P00352 1/20 0.41
CYP19A1 P11511 1/20 0.40
PRKCI P41743 1/20 0.40
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
FDPS P14324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21408418 0.85 TBXAS1 (0.58) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL21408577 0.85 TBXAS1 (0.58) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL1709955 0.80 TBXAS1 (0.53) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL8495419 0.79 TBXAS1 (0.60) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL18079807 0.78 TBXAS1 (0.50) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL9046908 0.78 TBXAS1 (0.50) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL23120204 0.77 TBXAS1 (0.50) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL181658 0.76
SCHEMBL21408488 0.76 TBXAS1 (0.47) TBXAS1TP53KDM4ETSHREGLN3
SCHEMBL21408486 0.76 TBXAS1 (0.47) TBXAS1TP53KDM4ETSHREGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-H972-H Direct positive color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US claimed
US-4966833-A USING HETEROCYCLIC NITROGEN CONTAINING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-10-30 US claimed
EP-0311110-A2 Direct positive color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-04-12 EP claimed
EP-0598241-B1 Lithographic printing material FUJI PHOTO FILM CO LTD (JP) 1998-02-04 EP disclosed
EP-0427225-B1 Direct positive color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0355661-B1 Direct positive image forming method FUJI PHOTO FILM CO LTD (JP) 1995-07-19 EP disclosed
US-5387483-A Developer containing silver halide solvent and hydroquinone; has pH up to 11.8 FUJI PHOTO FILM CO., LTD. (JP) 1995-02-07 US disclosed
EP-0249239-B1 Process for the formation of direct positive images FUJI PHOTO FILM CO LTD (JP) 1995-01-25 EP disclosed
EP-0601600-A2 Processing of lithographic printing material and developer used therein FUJI PHOTO FILM CO., LTD. (JP) 1994-06-15 EP disclosed
EP-0598241-A1 Lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-05-25 EP disclosed
EP-0283041-B1 DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 EP disclosed
US-4954427-A Development of light-sensitive material in the presence of a nucleating agent and a nuceation accelerator FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US disclosed
US-4952483-A NOVEL HYDRAZINE NUCLEATING AGENTS AND ACCELERATORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed
US-4933265-A NUCLEATION PROMOTER FUJI PHOTO FILM CO., LTD. (JP) 1990-06-12 US disclosed
EP-0343604-A2 Method of forming color images Fuji Photo Film Co., Ltd. (JP) 1989-11-29 EP disclosed
EP-0331185-A2 Silver halide photographic element for forming direct positive images and a method for forming said images FUJI PHOTO FILM CO., LTD. (JP) 1989-09-06 EP disclosed
EP-0318988-A1 Direct positive photographic light sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-07 EP disclosed
EP-0311110-A2 Direct positive color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-04-12 EP disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed
EP-0249239-A2 Process for the formation of direct positive images FUJI PHOTO FILM CO., LTD. (JP) 1987-12-16 EP disclosed