Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598256 | 0.80 | HTT (0.37) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8598859 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8600588 | 0.76 | KDM4E (0.38) | MAPTKDM4EHTT | |
| SCHEMBL8595645 | 0.76 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8601106 | 0.75 | PDE4A (0.35) | ALDH1A1LMNAMAPTKDM4EHTT | |
| SCHEMBL8597055 | 0.74 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8597309 | 0.71 | KMT2A (0.38) | LMNAMAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL8600118 | 0.71 | MEN1 (0.33) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8596102 | 0.71 | HCAR3 (0.42) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL8602563 | 0.70 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |