Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600637 | 1.00 | HDAC1 (0.34) | HDAC1HDAC8ALDH1A1PPARGPPARD | |
| SCHEMBL7557688 | 0.91 | PTGS2 (0.35) | HDAC1HDAC8ALDH1A1PPARGPPARD | |
| SCHEMBL7557685 | 0.91 | PTGS2 (0.35) | HDAC1HDAC8ALDH1A1PPARGPPARD | |
| SCHEMBL7557372 | 0.91 | PTGS2 (0.33) | HDAC1HDAC8ALDH1A1CYP3A4TP53 | |
| SCHEMBL7557378 | 0.91 | PTGS2 (0.33) | HDAC1HDAC8ALDH1A1CYP3A4TP53 | |
| SCHEMBL8049254 | 0.88 | HDAC1 (0.37) | HDAC1HDAC8ALDH1A1PPARGPPARD | |
| SCHEMBL8049250 | 0.88 | HDAC1 (0.37) | HDAC1HDAC8ALDH1A1PPARGPPARD | |
| SCHEMBL8602712 | 0.85 | NPC1 (0.33) | ALDH1A1TP53SMN1; SMN2KDM4EHPGD | |
| SCHEMBL8602711 | 0.85 | NPC1 (0.33) | ALDH1A1TP53SMN1; SMN2KDM4EHPGD | |
| SCHEMBL7559045 | 0.84 | ALDH1A1 (0.30) | ALDH1A1PPARGPPARDPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667384-B1 | Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0667384-A1 | Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-08-16 | — | — | EP | disclosed |