Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19402368 | 0.82 | MAPT (0.51) | L3MBTL1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL19402241 | 0.81 | MAPT (0.67) | L3MBTL1HCAR3MAPTPOLBALDH1A1 | |
| SCHEMBL15740729 | 0.80 | L3MBTL1 (0.53) | L3MBTL1HCAR3MAPTPOLBPKM | |
| SCHEMBL8598258 | 0.79 | L3MBTL1 (0.47) | L3MBTL1HCAR3MAPTPOLBPKM | |
| SCHEMBL10428303 | 0.79 | MAPT (0.63) | L3MBTL1HCAR3MAPTPOLBPKM | |
| SCHEMBL9796844 | 0.79 | MAPT (0.63) | L3MBTL1HCAR3MAPTPOLBPKM | |
| SCHEMBL8599060 | 0.77 | L3MBTL1 (0.45) | L3MBTL1HCAR3POLBLMNA | |
| SCHEMBL8595708 | 0.76 | GABRP (0.50) | L3MBTL1MAPTPOLBALDH1A1TDP1 | |
| SCHEMBL8597281 | 0.76 | SMN1; SMN2 (0.47) | L3MBTL1MAPTPOLBALDH1A1LMNA | |
| SCHEMBL8599737 | 0.76 | L3MBTL1 (0.49) | L3MBTL1HCAR3MAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |