Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413251 | 0.82 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8600919 | 0.80 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8995619 | 0.78 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7775837 | 0.76 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8780052 | 0.75 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21656702 | 0.75 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9852541 | 0.74 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL333133 | 0.74 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL333577 | 0.73 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15647665 | 0.72 | LMNA (0.39) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5725840-A | Steroidal ester contrast media for x-ray and magnetic resonance imaging | NYCOMED IMAGING AS (NO) | 1998-03-10 | — | — | US | disclosed |