Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995623 | 0.91 | LMNA (0.37) | LMNASMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL8995703 | 0.87 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21656702 | 0.86 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL333577 | 0.85 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL371082 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL15647665 | 0.83 | LMNA (0.39) | LMNASMN1; SMN2TSHR | |
| SCHEMBL332859 | 0.82 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL8752131 | 0.82 | LMNA (0.42) | LMNASMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL9076702 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL9413251 | 0.79 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559266-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1996-09-24 | — | — | US | disclosed |
| US-5416223-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1995-05-16 | — | — | US | disclosed |
| US-5370861-A | Iodinated esters contrast medium and use | NYCOMED IMAGING AS (NO) | 1994-12-06 | — | — | US | disclosed |
| EP-0452377-B1 | IODINATED ESTERS | NYCOMED IMAGING AS (NO) | 1994-09-21 | — | — | EP | disclosed |