Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | FCER2 | P06734 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798495 | 0.86 | ECE1 (0.45) | ECE1MMP1NPC1RAB9ACTSK | |
| SCHEMBL8872910 | 0.83 | ECE1 (0.52) | ECE1MMP1FCER2NPC1RAB9A | |
| SCHEMBL8872913 | 0.83 | ECE1 (0.52) | ECE1MMP1FCER2NPC1RAB9A | |
| SCHEMBL10793891 | 0.77 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL10793880 | 0.77 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL1458342 | 0.77 | ECE1 (0.55) | ECE1NPC1RAB9ACTSKPSMB5 | |
| SCHEMBL10797269 | 0.75 | LTA4H (0.51) | NPC1RAB9ACTSKCTSL | |
| SCHEMBL24252140 | 0.74 | NPC1 (0.51) | NPC1RAB9APSMB5 | |
| SCHEMBL10790971 | 0.74 | LTA4H (0.53) | NPC1RAB9A | |
| SCHEMBL8871593 | 0.73 | FCER2 (0.52) | MMP1FCER2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821668-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033165-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | disclosed |