Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | FCER2 | P06734 | 5/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872910 | 1.00 | ECE1 (0.52) | ECE1MMP1FCER2MMP2MMP3 | |
| SCHEMBL8601030 | 0.83 | ECE1 (0.49) | ECE1MMP1FCER2CTSKNPC1 | |
| SCHEMBL1458342 | 0.80 | ECE1 (0.55) | ECE1CTSKNPC1RAB9ACTSB | |
| SCHEMBL16450802 | 0.80 | NPC1 (0.54) | NPC1RAB9ACTSSCTSLPSMB5 | |
| SCHEMBL9714100 | 0.79 | ADAM17 (0.59) | MMP1MMP2MMP3 | |
| SCHEMBL9713913 | 0.79 | ADAM17 (0.59) | MMP1MMP2MMP3 | |
| SCHEMBL6798495 | 0.79 | ECE1 (0.45) | ECE1MMP1CTSKNPC1RAB9A | |
| SCHEMBL6808350 | 0.77 | MMP1 (0.54) | MMP1FCER2MMP2MMP3 | |
| SCHEMBL8871593 | 0.76 | FCER2 (0.52) | MMP1FCER2MMP2MMP3PSMB5 | |
| SCHEMBL8871600 | 0.76 | FCER2 (0.52) | MMP1FCER2MMP2MMP3PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703092-A | TREATING ARTHRITIS, OTHER INFLAMMATORY DISEASES MEDIATED BY MATRIX METALLOPROTEINASE AND/OR TUMOR NECROSIS FACTOR | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-12-30 | — | — | US | disclosed |