SCHEMBL860111

SCHEMBL860111

CCCON1C(=O)c2ccc(C(=O)c3ccc4c(c3)C(=O)N(OCCC)C4=O)cc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
ALDH1A1 P00352 7/20 0.50
TSHR P16473 1/20 0.49
POLB P06746 2/20 0.48
ENPP2 Q13822 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 1/20 0.46
APEX1 P27695 1/20 0.43
GAA P10253 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
NPC1 O15118 2/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14588693 0.80 GAA (0.46) LMNAALDH1A1POLBKMT2AMEN1
SCHEMBL860270 0.78 TDP1 (0.49) LMNAALDH1A1POLBKMT2AMEN1
SCHEMBL13622420 0.77 ALDH1A1 (0.63) LMNAALDH1A1TSHRKMT2AMEN1
SCHEMBL6625137 0.77 GAA (0.69) ALDH1A1POLBKMT2AMEN1GAA
SCHEMBL860092 0.76 ALDH1A1 (0.49) LMNAALDH1A1TSHRPOLBENPP2
SCHEMBL859702 0.76 ALDH1A1 (0.46) LMNAALDH1A1TSHRPOLBKMT2A
SCHEMBL13159268 0.76 POLB (0.78) LMNAALDH1A1TSHRPOLBENPP2
SCHEMBL23055337 0.75 LMNA (0.43) LMNAALDH1A1TSHRPOLBKMT2A
SCHEMBL13622430 0.75 ALDH1A1 (0.46) LMNAALDH1A1TSHRPOLBENPP2
SCHEMBL14582620 0.74 ALDH1A1 (0.50) LMNAALDH1A1TSHRPOLBENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2100731-B1 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORP (JP) 2012-06-20 EP disclosed
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
EP-2100731-A2 Lithographic printing plate precursor and method of lithographic printing Fujifilm Corporation (JP) 2009-09-16 EP disclosed