Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 13/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33377163 | 0.82 | PRKDC (0.56) | PRKDCPIK3CDPIK3CAPIK3CBCDK1 | |
| SCHEMBL24384617 | 0.79 | PRKDC (0.52) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28511289 | 0.79 | PRKDC (0.67) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28159119 | 0.78 | GAA (0.65) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8600213 | 0.75 | MAPT (0.54) | MEN1KMT2AMAPT | |
| SCHEMBL2419958 | 0.73 | PRKDC (0.67) | PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17804470 | 0.73 | PRKDC (0.67) | PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL14972404 | 0.73 | PRKDC (0.49) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30210341 | 0.73 | LGMN (0.53) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL23999520 | 0.73 | MAPKAPK2 (0.54) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |