Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534816 | 0.83 | MTNR1A (0.69) | MTNR1A | |
| SCHEMBL8659243 | 0.81 | MTNR1A (0.45) | MTNR1ASMN1; SMN2L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL8601819 | 0.80 | MTNR1A (0.44) | MTNR1ASMN1; SMN2L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL8601815 | 0.80 | MTNR1A (0.44) | MTNR1ASMN1; SMN2L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL8623895 | 0.80 | MTNR1A (0.44) | MTNR1ASMN1; SMN2L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL8599310 | 0.74 | MTNR1A (0.48) | MTNR1A | |
| SCHEMBL8597245 | 0.72 | HIF1A (0.52) | MTNR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7640335 | 0.71 | PLK1 (0.58) | CYP1A2CYP2C9CYP3A4NPSR1GAA | |
| SCHEMBL830122 | 0.71 | MTNR1A (0.67) | MTNR1A | |
| SCHEMBL8610419 | 0.70 | MTNR1A (0.58) | MTNR1ACYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819111-A1 | FUNGICIDAL COMPOUNDS | AgrEvo UK Limited (GB) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996029301-A1 | FUNGICIDAL COMPOUNDS | AGREVO UK LIMITED (GB) | 1996-09-26 | — | — | WO | disclosed |