SCHEMBL8601200

SCHEMBL8601200

COC(=O)/C=N/S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.53
PRSS1 P07477 2/20 0.53
PRSS2 P07478 2/20 0.53
PRSS3 P35030 2/20 0.53
LMNA P02545 3/20 0.51
GAA P10253 1/20 0.51
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
POLB P06746 4/20 0.44
HTT P42858 2/20 0.44
CYP2C9 P11712 2/20 0.42
CYP1A2 P05177 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8601203 1.00 F2 (0.53) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL7773013 0.90 F2 (0.44) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL7773010 0.90 F2 (0.44) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL12871278 0.84 LMNA (0.49) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL15705594 0.84 LMNA (0.49) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL11075418 0.78 SMN1; SMN2 (0.45) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL12652846 0.76 LMNA (0.51) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL17652439 0.75 ALDH1A1 (0.68) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL17652438 0.75 ALDH1A1 (0.68) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL19195144 0.75 ALDH1A1 (0.68) F2PRSS1PRSS2PRSS3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5785886-A ENHANCED BLEACH PERFORMANCE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1998-07-28 US disclosed
US-5653910-A SYNERGISTIC MIXTURE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO INC. (US) 1997-08-05 US disclosed
US-5463115-A Enhance bleaching action of peroxygen compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-10-31 US disclosed
US-5413733-A Bleaching LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-05-09 US disclosed
EP-0446982-B1 Low-temperature bleaching compositions UNILEVER NV (NL) 1994-10-26 EP disclosed
EP-0453003-B1 Bleach catalysts and compositions containing same UNILEVER NV (NL) 1994-10-05 EP disclosed
EP-0453003-A2 Bleach catalysts and compositions containing same UNILEVER N.V. (NL) 1991-10-23 EP disclosed
EP-0446982-A2 Low-temperature bleaching compositions UNILEVER N.V. (NL) 1991-09-18 EP disclosed
US-5047163-A Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-09-10 US disclosed
US-5041232-A Inlcudes peroxygen compound and surfactant LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-08-20 US disclosed