Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | FGB | P02675 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600843 | 0.90 | MEN1 (0.56) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL8603851 | 0.86 | TOP2B (0.62) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL8602603 | 0.85 | MEN1 (0.58) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL8602157 | 0.84 | NSD2 (0.50) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL8602144 | 0.84 | NSD2 (0.50) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL16344394 | 0.84 | TOP2B (0.64) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL11141088 | 0.81 | CYP19A1 (0.60) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL8604598 | 0.80 | MEN1 (0.49) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL8604601 | 0.80 | MEN1 (0.49) | NSD2MEN1POLBBLMKMT2A | |
| SCHEMBL111327 | 0.80 | TOP2B (0.55) | NSD2MEN1POLBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733880-A | ANTITUMOR AGENTS | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1998-03-31 | — | — | US | disclosed |
| EP-0721447-B1 | ANTHRACENE DERIVATIVES FOR USE AS ANTICANCER AGENT OR DYE | UNIV NAPIER (GB) | 1998-02-25 | — | — | EP | disclosed |
| WO-1995009149-A1 | ANTHRACENE DERIVATIVES FOR USE AS ANTICANCER AGENT OR DYE | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1995-04-06 | — | — | WO | disclosed |