Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604598 | 1.00 | MEN1 (0.49) | MEN1NSD2POLBBLMKMT2A | |
| SCHEMBL8628866 | 0.91 | MEN1 (0.51) | MEN1NSD2POLBBLMKMT2A | |
| SCHEMBL8628860 | 0.91 | MEN1 (0.51) | MEN1NSD2POLBBLMKMT2A | |
| SCHEMBL8603791 | 0.86 | MEN1 (0.52) | MEN1NSD2POLBBLMKMT2A | |
| SCHEMBL8699728 | 0.85 | HDAC8 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL8602157 | 0.84 | NSD2 (0.50) | MEN1NSD2POLBBLMKMT2A | |
| SCHEMBL8602144 | 0.84 | NSD2 (0.50) | MEN1NSD2POLBBLMKMT2A | |
| SCHEMBL8601249 | 0.80 | NSD2 (0.53) | MEN1NSD2POLBBLMKMT2A | |
| SCHEMBL12085491 | 0.80 | CHRNB2 (0.63) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL14359605 | 0.80 | CHRNB2 (0.63) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733880-A | ANTITUMOR AGENTS | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1998-03-31 | — | — | US | disclosed |
| EP-0721447-B1 | ANTHRACENE DERIVATIVES FOR USE AS ANTICANCER AGENT OR DYE | UNIV NAPIER (GB) | 1998-02-25 | — | — | EP | disclosed |
| WO-1995009149-A1 | ANTHRACENE DERIVATIVES FOR USE AS ANTICANCER AGENT OR DYE | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1995-04-06 | — | — | WO | disclosed |