Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4567587 | 0.84 | MAOB (0.59) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL28502948 | 0.84 | IDO1 (0.58) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL12582125 | 0.83 | IDO1 (0.56) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL6562098 | 0.83 | IDO1 (0.61) | IDO1AKR1C3RAB9AHTTHTR2A | |
| SCHEMBL10465292 | 0.81 | MAOB (0.56) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL37664 | 0.80 | HTR2A (0.62) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL11094406 | 0.79 | HTR2A (0.54) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL5445040 | 0.79 | MAOB (0.54) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL10801165 | 0.79 | HTR2A (0.58) | IDO1AKR1C3MAOBRAB9AHTT | |
| SCHEMBL5765803 | 0.79 | ALDH1A1 (0.57) | IDO1MAOBRAB9AHTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848467-B | Preparation method of asymmetric organic persulfate compound | 浙江大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-111848467-A | Preparation method of asymmetric organic persulfate compound | 浙江大学 | 2020-10-30 | — | — | CN | disclosed |
| EP-0723973-B1 | Nucleoside phosphorothioate derivatives, synthesis and use thereof | KING S COLLEGE LONDON (GB) | 1998-10-21 | — | — | EP | disclosed |
| US-5708161-A | Nucleoside phosphorothioate derivatives, synthesis and use thereof | KING'S COLLEGE LONDON (GB) | 1998-01-13 | — | — | US | disclosed |
| EP-0723973-A1 | Nucleoside phosphorothioate derivatives, synthesis and use thereof | KING'S COLLEGE LONDON (GB) | 1996-07-31 | — | — | EP | disclosed |