Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4478691 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7642731 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL29564384 | 0.74 | CYP11B1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL28313040 | 0.71 | CYP19A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL217508 | 0.71 | CYP19A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL30661221 | 0.70 | SIGMAR1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8465554 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL8927138 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL153451 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL3647258 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0692505-B1 | Process for procucing propylene block copolymers | MITSUBISHI CHEM CORP (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5623022-A | VAPOR PHASE; USING COORDINATION CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0692505-A2 | Process for procucing propylene block copolymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-17 | — | — | EP | disclosed |
| EP-0566349-A2 | Process for producing alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-10-20 | — | — | EP | disclosed |