Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 10/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599534 | 0.91 | LMNA (0.41) | LMNAITGB1ITGA4TYK2PTGES | |
| SCHEMBL8601960 | 0.88 | LMNA (0.41) | LMNAITGB1ITGA4PTGESMEN1 | |
| SCHEMBL8599739 | 0.84 | KMT2A (0.41) | LMNAPTGESKMT2A | |
| SCHEMBL8596747 | 0.84 | LMNA (0.42) | LMNAPTGES | |
| SCHEMBL8598365 | 0.83 | TYK2 (0.44) | TYK2PTGESLCKMEN1KMT2A | |
| SCHEMBL8602408 | 0.81 | TP53 (0.39) | LMNAITGB1ITGA4TYK2PTGES | |
| SCHEMBL8598941 | 0.80 | TYK2 (0.43) | TYK2PTGESLCKMEN1KMT2A | |
| SCHEMBL8597312 | 0.79 | TP53 (0.43) | TYK2PTGESLCKMEN1KMT2A | |
| SCHEMBL8598383 | 0.79 | PTGES (0.44) | PTGESKMT2A | |
| SCHEMBL8597841 | 0.79 | PTGES (0.37) | TYK2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |