Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.63 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602292 | 0.87 | SLC22A12 (0.64) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| Hydrochloric Acid SCHEMBL8601437 | 0.86 | SLC22A12 (0.62) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8600636 | 0.84 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8598408 | 0.80 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8604855 | 0.78 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8605195 | 0.78 | SLC22A12 (0.47) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8605723 | 0.77 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8601159 | 0.77 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8604518 | 0.77 | SLC22A12 (0.65) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8601793 | 0.76 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |