Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.64 |
| ▸ | PDE4A | P27815 | 5/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8601437 | 0.99 | SLC22A12 (0.62) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601435 | 0.87 | PDE4A (0.63) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600636 | 0.85 | PDE4A (0.57) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604518 | 0.81 | SLC22A12 (0.65) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599922 | 0.79 | SLC22A12 (0.74) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1552940 | 0.78 | SLC22A12 (0.58) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8598410 | 0.78 | SLC22A12 (0.72) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11976856 | 0.78 | SLC22A12 (1.00) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13578013 | 0.78 | SLC22A12 (0.61) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1552793 | 0.77 | PDE4A (0.62) | SLC22A12PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |