Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19510189 | 0.86 | ALDH1A1 (0.44) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8602292 | 0.85 | SLC22A12 (0.64) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| Hydrochloric Acid SCHEMBL8601437 | 0.84 | SLC22A12 (0.62) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8601435 | 0.84 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL1554558 | 0.80 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL11976857 | 0.80 | SLC22A12 (0.75) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL2806053 | 0.80 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL1552835 | 0.79 | SLC22A12 (0.46) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL1553503 | 0.79 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL8602333 | 0.79 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |