Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468490 | 0.91 | BRD4 (0.42) | BRD4MAOBAPLNRPDE3BPDE3A | |
| SCHEMBL7463464 | 0.86 | HSD17B10 (0.44) | BRD4USP2GAAHSD17B10PARP1 | |
| SCHEMBL7473275 | 0.83 | KDM4E (0.41) | BRD4GAAMAOBPDE3BPDE3A | |
| SCHEMBL7472419 | 0.83 | PARP1 (0.49) | BRD4GAAHSD17B10PARP1MAPK1 | |
| SCHEMBL7472191 | 0.82 | KMT2A (0.38) | BRD4GAAHSD17B10L3MBTL1MAPK1 | |
| SCHEMBL7476305 | 0.81 | ALOX5 (0.45) | USP2GAAHSD17B10PARP1L3MBTL1 | |
| SCHEMBL10358558 | 0.81 | BRD4 (0.46) | BRD4USP2GAAMAOBPDE3B | |
| SCHEMBL7471034 | 0.76 | KMT2A (0.45) | BRD4GAAHSD17B10L3MBTL1MAPK1 | |
| SCHEMBL7472662 | 0.75 | L3MBTL1 (0.43) | BRD4USP2GAAHSD17B10L3MBTL1 | |
| SCHEMBL7472656 | 0.73 | USP2 (0.33) | USP2GAAHSD17B10PARP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |