Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8597848 | 0.92 | SIRT1 (0.40) | GRIA1SIRT1SIRT6PAOXSIRT2 | |
| Trifluoroacetic Acid SCHEMBL8602931 | 0.91 | NPY4R (0.35) | NPY4RITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL8600634 | 0.91 | NPY4R (0.35) | NPY4RITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8601060 | 0.82 | ACHE (0.33) | GRIA1SIRT1SIRT6NPY4R | |
| Trifluoroacetic Acid SCHEMBL9173127 | 0.75 | HDAC6 (0.51) | HDAC6PAOX | |
| Trifluoroacetic Acid SCHEMBL9178312 | 0.75 | HDAC6 (0.51) | HDAC6PAOX | |
| Trifluoroacetic Acid SCHEMBL9175468 | 0.74 | HDAC6 (0.43) | GRIA1HDAC6NPY4RPAOX | |
| Trifluoroacetic Acid SCHEMBL9178492 | 0.74 | HDAC6 (0.43) | HDAC6NPY4RITGB3ITGA2BPAOX | |
| Trifluoroacetic Acid SCHEMBL9181152 | 0.74 | HDAC6 (0.43) | GRIA1HDAC6NPY4RPAOX | |
| Tresperimus SCHEMBL9173994 | 0.74 | HDAC6 (0.43) | HDAC6NPY4RITGB3ITGA2BPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733928-A | IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-03-31 | — | — | US | disclosed |