Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569083 | 0.88 | MMP2 (0.43) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8597525 | 0.88 | KMT2A (0.41) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8597093 | 0.87 | MMP2 (0.42) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8601890 | 0.87 | TNF (0.46) | SMN1; SMN2RAB9AKMT2AMEN1HTT | |
| SCHEMBL8599397 | 0.87 | MEN1 (0.41) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL8603024 | 0.87 | POLB (0.41) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8600749 | 0.86 | MEN1 (0.40) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL8603647 | 0.86 | MEN1 (0.40) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8602120 | 0.86 | PTGES (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8597119 | 0.86 | MEN1 (0.43) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |