Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600713 | 0.87 | PIK3CD (0.34) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL8603226 | 0.87 | PIK3CA (0.33) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL8602841 | 0.85 | GABRA1 (0.33) | — | |
| SCHEMBL8601011 | 0.84 | CYP2D6 (0.34) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL8603734 | 0.83 | PIK3CD (0.31) | PIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL8599019 | 0.83 | PTAFR (0.31) | — | |
| SCHEMBL8601045 | 0.81 | CYP2D6 (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL8597697 | 0.81 | CYP2D6 (0.35) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL8602701 | 0.74 | SQOR (0.34) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL8597874 | 0.73 | CYP2D6 (0.32) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |