Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15416672 | 0.87 | LMNA (0.67) | NPSR1TDP1PTGS2LMNAHTT | |
| SCHEMBL13779968 | 0.84 | LMNA (0.67) | NPSR1TDP1PTGS2LMNAHTT | |
| SCHEMBL29724013 | 0.83 | NPSR1 (1.00) | NPSR1TDP1PTGS2LMNAHTT | |
| SCHEMBL2876672 | 0.80 | KDM4E (0.60) | LMNAHTTMAPK1POLBKDM4E | |
| SCHEMBL6846644 | 0.80 | MAPK1 (0.51) | NPSR1TDP1PTGS2LMNAHTT | |
| Hydrochloric Acid SCHEMBL8600514 | 0.80 | MAPK1 (0.64) | NPSR1TDP1LMNAHTTMAPK1 | |
| SCHEMBL15473947 | 0.80 | LMNA (0.61) | TDP1PTGS2LMNAHTTGRIN2B | |
| SCHEMBL20458926 | 0.80 | LMNA (0.58) | NPSR1TDP1PTGS2LMNAHTT | |
| SCHEMBL15471365 | 0.77 | LMNA (0.58) | NPSR1TDP1PTGS2LMNAHTT | |
| SCHEMBL13039592 | 0.76 | LMNA (0.60) | PTGS2LMNAHTTGRIN2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |