Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572419 | 0.97 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL8601621 | 0.88 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL8603217 | 0.87 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8603112 | 0.82 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL8633013 | 0.81 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8649978 | 0.79 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604717 | 0.79 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8601928 | 0.78 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600001 | 0.74 | CNR1 (0.40) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL8601691 | 0.74 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |