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Sugi Predict / Compounds / SCHEMBL8602163

SCHEMBL8602163

SCHEMBL8602163

CCCN(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)c1nn(CCc2ccccc2)c(-c2ccccc2C)c1C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ AGT P01019 1/20 0.41
▸ AGTR1 P30556 18/20 0.39
▸ AGTR2 P50052 18/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8529152 0.90 AGT (0.42) AGTAGTR1AGTR2
SCHEMBL8600996 0.90 AGT (0.42) AGTAGTR1AGTR2
SCHEMBL8532658 0.90 AGT (0.43) AGTAGTR1AGTR2
SCHEMBL8529272 0.87 AGT (0.42) AGTAGTR1AGTR2
SCHEMBL8533668 0.83 AGTR1 (0.45) AGTAGTR1AGTR2
SCHEMBL9590962 0.82 AGTR1 (0.54) AGTAGTR1AGTR2
SCHEMBL9296555 0.81 AGTR1 (0.54) AGTAGTR1AGTR2
SCHEMBL9296257 0.81 AGT (0.42) AGTAGTR1AGTR2
SCHEMBL9589082 0.79 AGTR1 (0.52) AGTAGTR1AGTR2
SCHEMBL9542915 0.79 AGT (0.46) AGTAGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840909-A Pyrazole derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-11-24 — — US disclosed
US-5721264-A EXHIBIT ANTAGONISTIC EFFECT AGAINST ANGIOTENSIN II; USEFUL FOR PREVENTION AND REMEDY OF HYPERTENSION, CONGESTIVE HEARTFAILURE, CHRONIC RENAL INSUFFICIENCY, ALDOSTERONISM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-24 — — US disclosed
EP-0693480-A1 PYRAZOLE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-01-24 — — EP disclosed