Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 19/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 14/20 | 0.45 |
| ▸ | AGT | P01019 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296555 | 0.91 | AGTR1 (0.54) | AGTR1AGTR2AGT | |
| SCHEMBL8529591 | 0.87 | AGTR1 (0.43) | AGTR1AGTR2AGT | |
| SCHEMBL8529152 | 0.84 | AGT (0.42) | AGTR1AGTR2AGT | |
| SCHEMBL8600996 | 0.84 | AGT (0.42) | AGTR1AGTR2AGT | |
| SCHEMBL8532658 | 0.84 | AGT (0.43) | AGTR1AGTR2AGT | |
| SCHEMBL9589082 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2AGT | |
| SCHEMBL9591500 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8602163 | 0.83 | AGT (0.41) | AGTR1AGTR2AGT | |
| SCHEMBL9545115 | 0.83 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9590162 | 0.83 | AGTR1 (0.54) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846991-A | Pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5840909-A | Pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5817828-A | HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS; VISION DEFECTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5721264-A | EXHIBIT ANTAGONISTIC EFFECT AGAINST ANGIOTENSIN II; USEFUL FOR PREVENTION AND REMEDY OF HYPERTENSION, CONGESTIVE HEARTFAILURE, CHRONIC RENAL INSUFFICIENCY, ALDOSTERONISM | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0693480-A1 | PYRAZOLE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |