Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659793 | 0.76 | TSHR (0.38) | ALDH1A1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL3706530 | 0.75 | GAA (0.41) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL8017733 | 0.75 | GAA (0.44) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL8602207 | 0.73 | ALDH1A1 (0.37) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL4945883 | 0.72 | GAA (0.42) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL4070110 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL9015895 | 0.70 | KMT2A (0.42) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL4681303 | 0.70 | HPGD (0.45) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL10712715 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL11599011 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAGAAMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | claimed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | claimed |