Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015895 | 0.88 | KMT2A (0.42) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL10712715 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL27328001 | 0.79 | GAA (0.37) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL11599011 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL4945883 | 0.76 | GAA (0.42) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL3706530 | 0.75 | GAA (0.41) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL8017733 | 0.75 | GAA (0.44) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL15526685 | 0.74 | THRB (0.43) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL8602207 | 0.73 | ALDH1A1 (0.37) | ALDH1A1HPGDLMNAGAAMTNR1A | |
| SCHEMBL28074532 | 0.72 | HDAC1 (0.43) | ALDH1A1HPGDGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079449-A2 | PHENYLALKYLAMINO CARBAMATE COMPOSITIONS | Janssen Pharmaceutica, N.V. (BE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008048801-A3 | PHENYLALKYLAMINO CARBAMATE COMPOSITIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008048801-A2 | PHENYLALKYLAMINO CARBAMATE COMPOSITIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-04-24 | — | — | WO | disclosed |
| EP-0747036-A2 | A method of coloring hair with, and hair coloring compositions comprising, sulfo-containing water dispersible colored polymers | Bristol-Myers Squibb Company (US) | 1996-12-11 | — | — | EP | disclosed |