Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403523 | 0.77 | — | — | |
| SCHEMBL10402933 | 0.77 | RPS6KA3 (0.33) | HSD17B10RAB9A | |
| SCHEMBL10404354 | 0.74 | SMN1; SMN2 (0.37) | CYP1A2CYP3A4CYP2C19KMT2AL3MBTL1 | |
| SCHEMBL10402932 | 0.73 | RPS6KA3 (0.33) | — | |
| SCHEMBL10403096 | 0.71 | — | — | |
| SCHEMBL10404352 | 0.70 | SMN1; SMN2 (0.35) | KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL2606389 | 0.67 | MYC (0.44) | FFAR1CYP1A2HSD17B10CYP3A4CYP2C19 | |
| SCHEMBL9353656 | 0.64 | DAO (0.46) | FFAR1PHGDHCYP1A2HSD17B10CYP3A4 | |
| SCHEMBL2213224 | 0.63 | HPGD (0.56) | FFAR1CYP1A2HSD17B10KMT2AKDM4E | |
| SCHEMBL28057627 | 0.63 | KEAP1 (0.38) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432774-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING URIC ACID LEVELS | Ardea Biosciences, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135530-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING URIC ACID LEVELS | ARDEA BIOSCIENCES, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| EP-0012868-A1 | 1,2,3-Thiadiazol-5-yl-thioglycolic acid, its derivatives and process for their preparation | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | disclosed |
| EP-0012868-A1 | 1,2,3-Thiadiazol-5-yl-thioglycolic acid, its derivatives and process for their preparation | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | disclosed |