Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | YAP1 | P46937 | 1/20 | 0.30 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404354 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTHTTALDH1A1GFER | |
| SCHEMBL10402932 | 0.83 | RPS6KA3 (0.33) | RPS6KA3 | |
| SCHEMBL860259 | 0.70 | FFAR1 (0.39) | ALDH1A1POLBKMT2ARAB9A | |
| SCHEMBL10403520 | 0.70 | — | — | |
| SCHEMBL10402401 | 0.69 | MTNR1A (0.33) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BNPC1 | |
| SCHEMBL10402850 | 0.66 | HPGD (0.45) | SMN1; SMN2MAPTALDH1A1POLBKMT2A | |
| SCHEMBL10402679 | 0.65 | RAB9A (0.49) | SMN1; SMN2HTTALDH1A1MEN1LMNA | |
| SCHEMBL10404003 | 0.64 | ALDH1A1 (0.37) | SMN1; SMN2MAPTHTTALDH1A1GFER | |
| SCHEMBL10401986 | 0.63 | MTNR1A (0.71) | SMN1; SMN2HTTALDH1A1MEN1LMNA | |
| SCHEMBL10403664 | 0.62 | KMT2A (0.53) | SMN1; SMN2MAPTALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |