Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605051 | 0.97 | HDAC1 (0.42) | HRASESR1ESR2SMN1; SMN2MAPT | |
| SCHEMBL9028656 | 0.86 | HRAS (0.49) | HRASESR1ESR2SMN1; SMN2MAPT | |
| SCHEMBL7467780 | 0.83 | HRAS (0.48) | HRASESR1ESR2SMN1; SMN2MAPT | |
| SCHEMBL7467693 | 0.75 | HRAS (0.47) | HRASESR1ESR2MAPTHDAC1 | |
| Hydrochloric Acid SCHEMBL7470484 | 0.75 | HRAS (0.47) | HRASESR1ESR2MAPTHDAC1 | |
| SCHEMBL7472023 | 0.73 | HRAS (0.51) | HRASESR1ESR2MAPTEGFR | |
| SCHEMBL7471663 | 0.72 | HRAS (0.46) | HRASESR1ESR2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL7466261 | 0.72 | HRAS (0.49) | HRASESR1ESR2MAPTALDH1A1 | |
| SCHEMBL8987569 | 0.72 | MAPT (0.53) | SMN1; SMN2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL8298671 | 0.71 | HRAS (0.46) | HRASESR1ESR2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |