Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | COMT | P21964 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987549 | 0.90 | MAPT (0.49) | MAPTMEN1KMT2AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8987608 | 0.86 | MAPT (0.48) | MAPTMEN1KMT2AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8987491 | 0.84 | KDM4E (0.48) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987520 | 0.83 | MMP13 (0.54) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987648 | 0.81 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987636 | 0.81 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987815 | 0.80 | HPSE (0.44) | MAPTMEN1KMT2AKDM4EPOLB | |
| Iodide SCHEMBL8987612 | 0.80 | MAPT (0.46) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987682 | 0.80 | MAPT (0.46) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987640 | 0.80 | MAPT (0.50) | MAPTMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719765-A2 | Phenylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-03 | — | — | EP | disclosed |