Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602762 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| SCHEMBL1077276 | 0.89 | TSHR (0.51) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| SCHEMBL7382311 | 0.89 | TSHR (0.51) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| SCHEMBL10137745 | 0.89 | TSHR (0.51) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| SCHEMBL9636938 | 0.89 | TSHR (0.51) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| SCHEMBL23485377 | 0.89 | TSHR (0.51) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| SCHEMBL21961574 | 0.89 | TSHR (0.51) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| Hydrochloric Acid SCHEMBL7382305 | 0.88 | TSHR (0.53) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| Hydrochloric Acid SCHEMBL1784263 | 0.88 | TSHR (0.53) | ALDH1A1TSHRHTR2CCTSCBACE1 | |
| SCHEMBL6167045 | 0.86 | CTSC (0.46) | ALDH1A1TSHRHTR2CCTSCBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828851-A2 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996035805-A2 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1996-11-14 | — | — | WO | disclosed |