Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087722 | 0.79 | MAPT (0.54) | MAPTKDM4ECYP3A4LMNAMEN1 | |
| SCHEMBL29852620 | 0.79 | MAPT (0.54) | MAPTKDM4ECYP3A4LMNAMEN1 | |
| SCHEMBL8601135 | 0.77 | PSMD14 (0.51) | MAPTKDM4EPSMD14CYP3A4LMNA | |
| SCHEMBL20653883 | 0.74 | MAPT (0.52) | MAPTKDM4EPSMD14CYP3A4LMNA | |
| SCHEMBL7821404 | 0.71 | MAPT (0.58) | MAPTKDM4ECYP3A4LMNAMEN1 | |
| SCHEMBL8624 | 0.71 | CYP3A4 (0.49) | MAPTKDM4ECYP3A4LMNAMEN1 | |
| SCHEMBL8808071 | 0.71 | KDM4E (0.52) | KDM4EMEN1HTTKMT2AHIF1A | |
| SCHEMBL1498128 | 0.71 | MAPT (0.58) | MAPTKDM4ECYP3A4LMNAMEN1 | |
| SCHEMBL13166532 | 0.70 | CYP3A4 (0.47) | MAPTKDM4ECYP3A4LMNAMEN1 | |
| SCHEMBL2926836 | 0.70 | MAPT (0.89) | MAPTKDM4ECYP3A4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |