SCHEMBL2087722

SCHEMBL2087722

c1cnc2ccc3cc[nH]c3c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP3A4 P08684 1/20 0.53
LMNA P02545 2/20 0.52
AXL P30530 1/20 0.46
NUDT1 P36639 1/20 0.46
MEN1 O00255 1/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
HTT P42858 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
HIF1A Q16665 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.39
NR4A2 P43354 1/20 0.39
EGFR P00533 1/20 0.38
ERN1 O75460 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29852620 1.00 MAPT (0.54) MAPTKDM4ECYP3A4LMNAAXL
SCHEMBL8624 0.88 CYP3A4 (0.49) MAPTKDM4ECYP3A4LMNAAXL
Imidazole SCHEMBL144265 0.88 CYP3A4 (0.42) MAPTKDM4ECYP3A4LMNAAXL
SCHEMBL13166532 0.86 CYP3A4 (0.47) MAPTKDM4ECYP3A4LMNAAXL
SCHEMBL146383 0.81 CYP3A4 (0.44) MAPTKDM4ECYP3A4LMNAAXL
Quinoline SCHEMBL10490755 0.80 ALDH1A1 (0.52) MAPTKDM4ECYP3A4LMNAAXL
SCHEMBL31358268 0.80 CYP3A4 (0.43) MAPTKDM4ECYP3A4LMNAAXL
Fluoride SCHEMBL28071548 0.80 CYP3A4 (0.43) MAPTKDM4ECYP3A4LMNAAXL
SCHEMBL29190842 0.80 CYP3A4 (0.43) MAPTKDM4ECYP3A4LMNAAXL
SCHEMBL27715530 0.80 CYP3A4 (0.43) MAPTKDM4ECYP3A4LMNAAXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185329-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-04-22 EP claimed
US-20260059937-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT EACH INCLUDING THE SAME, AND THE CONDENSED CYCLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2026-02-26 US claimed
US-20250380610-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2025-12-11 US claimed
EP-4638448-A1 CONJUGATES COMPRISING ANTIFUNGALS AND CASEIN KINASE (CK1) INHIBITORS AND METHODS OF USE THEREOF Bright Angel Therapeutics Inc. (CA) 2025-10-29 EP claimed
US-12448389-B2 BRM targeting compounds and associated methods of use PRELUDE THERAPEUTICS INCORPORATED (US) 2025-10-21 US claimed
US-20250313818-A1 CRISPR-Cas Effector Polypeptides and Methods of Use Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-10-09 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-20250066799-A1 UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2025-02-27 US claimed
WO-2025041085-A1 DUAL NUCLEASE SYSTEMS FOR GENE EDITING, METHODS OF PRODUCING AND USING SAME SPECIFIC BIOLOGICS INC. (CA) 2025-02-27 WO claimed
US-12215343-B2 Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-04 US claimed
EP-4041249-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES The Scripps Research Institute (US) 2022-08-17 EP claimed
US-20220243244-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES NATIONAL INSTITUTES OF HEALTH 2022-08-04 US claimed
US-11401532-B2 Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-02 US claimed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN claimed
CN-109912592-B Compound containing pyridoindole and application of compound in organic electroluminescent device 江苏三月科技股份有限公司 2022-05-17 CN claimed
WO-2022099117-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE PRELUDE THERAPEUTICS INCORPORATED (US) 2022-05-12 WO claimed
WO-2022097070-A1 GENE EDITING WITH A MODIFIED ENDONUCLEASE SPECIFIC BIOLOGICS INC. (CA) 2022-05-12 WO claimed
US-11274318-B2 Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-15 US claimed
EP-3560917-A1 POLYMER CONTAINING FURAN CROSSLINKING GROUP AND USE THEREOF Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2019-10-30 EP claimed
US-6472402-B1 Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives NEUROGEN CORPORATION 2002-10-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250380610-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE LEF1, L1CAM, EMC1 MAPT 2447/4885KDM4E 1399/4885CYP3A4 1253/4885
US-20250066799-A1 UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE RNGTT, SPOUT1, NPEPPS MAPT 3580/4885KDM4E 4046/4885CYP3A4 4881/4885
US-20260059937-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT EACH INCLUDING THE SAME, AND THE CONDENSED CYCLIC COMPOUND SCO2, CCNE2, RER1 MAPT 4598/4885KDM4E 3927/4885CYP3A4 1530/4885
US-12448389-B2 BRM targeting compounds and associated methods of use ADRM1, BRDT, RBX1 MAPT 1598/4885KDM4E 2075/4885CYP3A4 4354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.