SCHEMBL8604237

SCHEMBL8604237

O=C1CCc2ccccc2SO1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.39
CYP2A6 P11509 2/20 0.38
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
NPC1 O15118 1/20 0.34
MAPK13 O15264 1/20 0.34
MAPK12 P53778 1/20 0.34
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
CYP1A2 P05177 1/20 0.33
MAOA P21397 3/20 0.32
MAOB P27338 2/20 0.32
ACHE P22303 1/20 0.31
AKR1B1 P15121 1/20 0.31
TSHR P16473 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1588593 0.72 CA12 (0.35) KDM4EALDH1A1HPGDMAOAMAOB
SCHEMBL4511352 0.69 TSHR (0.42) CYP2A6ALDH1A1HPGDMAOAMAOB
SCHEMBL31510121 0.69 TSHR (0.58) CES1CYP2A6KDM4EHPGDNPC1
SCHEMBL29190731 0.69 TSHR (0.58) CES1CYP2A6KDM4EHPGDNPC1
SCHEMBL29836089 0.68 ALDH1A1 (0.47) CES1CYP2A6KDM4EALDH1A1HPGD
SCHEMBL6238887 0.68 ALDH1A1 (0.47) CES1CYP2A6KDM4EALDH1A1HPGD
SCHEMBL4488551 0.68 ALDH1A1 (0.50) CES1CYP2A6KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL28694708 0.67 ALDH1A1 (0.46) CES1CYP2A6KDM4EALDH1A1HPGD
Dihydrocoumarin SCHEMBL29350292 0.64 MAOB (0.50) CES1CYP2A6KDM4EHPGDNPC1
Dihydrocoumarin SCHEMBL28795 0.64 MAOB (0.50) CES1CYP2A6KDM4EHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817835-A COCATALYSTS IN CHLORINATION OF TOLUENE OCCIDENTAL CHEMICAL CORPORATION (US) 1998-10-06 US disclosed
US-5817835-A COCATALYSTS IN CHLORINATION OF TOLUENE OCCIDENTAL CHEMICAL CORPORATION (US) 1998-10-06 US disclosed