Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MIF | P14174 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545250 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL38809 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL29654078 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL9812377 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL9835183 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL7841921 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL9059816 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL31252817 | 0.82 | ESRRG (0.48) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL8470095 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MIFALOX15NR1I2LMNA | |
| SCHEMBL10495896 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MIFALOX15NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5393923-A | Enzyme inhibitor; treating arthritis and inflammation | WARNER-LAMBERT COMPANY (US) | 1995-02-28 | — | — | US | disclosed |