Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MIF | P14174 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27952265 | 0.88 | LMNA (0.46) | ALDH1A1LMNAMIFALOX15HSD17B10 | |
| SCHEMBL19665480 | 0.84 | CA12 (0.55) | ALDH1A1LMNAMIFALOX15HSD17B10 | |
| SCHEMBL8604332 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNAMIFALOX15HSD17B10 | |
| SCHEMBL24436717 | 0.82 | CES2 (0.47) | ALDH1A1LMNAMIFHTTHPGD | |
| SCHEMBL25584048 | 0.80 | CSNK2A1 (0.42) | ALDH1A1LMNAHSD17B10TYRTSHR | |
| SCHEMBL17935123 | 0.79 | CA12 (0.62) | ALDH1A1LMNAMIFALOX15HSD17B10 | |
| SCHEMBL12251418 | 0.78 | PTGDR2 (0.46) | ALDH1A1LMNAALOX15CYP2C9HTT | |
| SCHEMBL12251320 | 0.78 | NPC1 (0.44) | ALDH1A1LMNAHTTMAPK1GAA | |
| SCHEMBL25584049 | 0.78 | MAPT (0.41) | ALDH1A1LMNAALOX15HSD17B10CYP2C9 | |
| SCHEMBL16520525 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNAMIFHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237986-B1 | FLAVONE CARBOXYLIC ACID DERIVATIVES | Shudo, Koichi, Prof. Dr. (JP) | 1991-10-02 | — | — | EP | disclosed |
| US-4925979-A | INTERMEDIATES FOR ANTILEUKEMIA AGENTS, CELL DIFFERENTIATION | SHIONOGI & CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4831052-A | DIFFERENTIATION-INDUCING AGENT FOR CERTAIN MALIONANT CELLS | SHIONOGI & CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0237986-A2 | Flavone carboxylic acid derivatives | Shudo, Koichi, Prof. Dr. (JP) | 1987-09-23 | — | — | EP | disclosed |