Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733475 | 0.83 | HSD17B3 (0.52) | HSD17B3PTPN1NPC1RAB9AKDM4E | |
| SCHEMBL5458729 | 0.83 | TSHR (0.52) | ALDH1A1HPGD | |
| SCHEMBL507049 | 0.83 | NPC1 (0.58) | NPC1RAB9AALDH1A1GAATDP1 | |
| SCHEMBL6656619 | 0.82 | HSD17B3 (0.50) | HSD17B3PTPN1NPC1RAB9AKDM4E | |
| SCHEMBL10021822 | 0.81 | TPMT (0.46) | NPC1RAB9AMAPT | |
| SCHEMBL12243016 | 0.81 | RAB9A (0.61) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL14041429 | 0.81 | LMNA (0.46) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL11989218 | 0.81 | NPC1 (0.55) | PTPN1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL10453790 | 0.81 | HAO1 (0.46) | HSD17B3NPC1RAB9AALDH1A1GAA | |
| SCHEMBL10452926 | 0.81 | GSK3B (0.57) | NPC1RAB9AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220032256-A1 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation | 2022-02-03 | — | — | US | disclosed |
| US-RE46170-E1 | Insulin derivatives | NOVO NORDISK A/S (DK) | 2016-10-04 | — | — | US | disclosed |
| US-RE46170-E1 | Insulin derivatives | NOVO NORDISK A/S (DK) | 2016-10-04 | — | — | US | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5393923-A | Enzyme inhibitor; treating arthritis and inflammation | WARNER-LAMBERT COMPANY (US) | 1995-02-28 | — | — | US | disclosed |